Publications
Natsuki Mori, Aisya Syahmina, Hitomi Mizuno-Nakamura, Luc Teboul, Masaaki
Yoneuchi, Toyonobu Usuki*
"Extraction of Caffeoylqunic Acids (CQAs) from Sweet Potato Leaves
and Stems"
European Food Research and Technology 2024, in press.
Christian Nanga Chick, Francois Eya'ane Meva,* Phillippe Belle Ebanda Kedi,
Toyonobu Usuki*
"Green Synthesis of Silver Nanoparticles with Cyclosorus dentatus and Nephrolepis biserrata and their Antioxidant, Anti-Inflammatory Studies"
Nano Select 2024, in press.
Ryosuke Shigeta, Takahiro Suzuki, Kazuki Kaneko, Hiroaki Tanaka, Ibuki
Haishima, Kanata Norio, Ayano Tanaka-Yanuma, Toyonobu Usuki*
"Total Synthesis of Jamaicamide B"
Organic & Biomolecular Chemistry 2024, 22, 4637-4640.
【Selected as front cover】
Lokadi Pierre Luhata, Yusuke Yoshida, Toyonobu Usuki*
"Natural Products from Odontonema strictum Promote Neurite Outgrowth in Neuronal PC12 Cells"
Bioorganic Chemistry 2024, 147, 107389.
Eri Tanaka, Yukie Yokota, Masamitsu Urakawa, Toyonobu Usuki*
"Extraction of Oleanolic Acid from Wine Pomace using Betaine-Based
Deep Eutectic Solvents"
European Food Research and Technology 2024, in press.
Hiroaki Tanaka, Seiya Miyagi, Tomoko Morita, Hiroaki Ishii, Natsuki Mori,
Kaho Oishi, Takemasa Sakaguchi,* Toyonobu Usuki*
"Synthesis and Cell-Based Evaluation of Umifenovir Analogues as Anti-SARS-CoV-2
Agents"
Helvetica Chimica Acta 2024, 107, e202300208.
Ryosuke Tashiro, Riki Anzawa, Tomoo Inoue,* Ayame Mikagi, Dan Ozaki, Keita
Tominaga, Takashi Inoue, Tomohisa Ishida, Miki Fujimura, Toyonobu Usuki,*
Hidenori Endo, Kuniyasu Niizuma,* Teiji Tominaga
"The Prognostic Values of Plasma Desmosines, Crosslinking Molecules
of Elastic Fibers, in the Disease Progression of Moyamoya Disease"
Bioorganic & Medicinal Chemistry 2024, 100, 117602.
Lokadi Pierre Luhata, Yoshiko Iizuka, Ryotaro Eda, Hiroshi Uchida, Christian
Nanga Chick, Makoto Kubo, Toyonobu Usuki*
"Synthesis of Property of Silver Nanoparticles with Verbacoside"
Chemistry Letters 2024, 53, upad024.
Kaho Oishi, Christian Nanga Chick, Hiroto Yanuma, Toyonobu Usuki*
"Synthesis of Neodesmosine-d4 and Quantitative LC-MS/MS Analysis of Neodesmosine in Biological Samples"
Tetrahedron Letters 2024, 134, 154853.
Shogo Satoh, Daria A. Baut, Moena Hirao, Daisuke Watanabe, Rina Suzuki,
Toyonobu Usuki*
"Synthesis of Ser-Ala-Ala Cyclic Desmosine"
Synthesis 2024, 56, 763-770.
Ryosuke Shigeta, Seiya Miyagi, Toyonobu Usuki*
"Synthesis of Desmosine-KLH Conjugated Antigen via IsoChichibabin
Pyridinium Synthesis"
Tetrahedron Letters 2023, 132, 154805.
Tomoyuki Kojima, Takashi Nakamura, Junichi Saito, Yuko Hidaka, Taisuke
Akimoto, Hana Inoue, Christian Nanga Chick, Toyonobu Usuki, Makoto Kaneko,
Etsuko Miyagi, Yoshihiro Ishikawa, Utako Yokoyama*
"Hydrostatic Pressure under Hypoxia Facilitates Fabrication of Tissue-Engineered
Vascular Grafts Drived from Human Vascular Smooth Muscle Cells in Vitro"
Acta Biomaterialia 2023, 171, 209-222.
Lokadi Pierre Luhata, Moena Hirao, Natsuki Mori, Toyonobu Usuki*
"Chemical Composition and Antioxidant Activity of the Hexane Fraction
from Leaf Extracts of Odonntonema strictum"
American Journal of Essential Oils and Natural Products 2023, 11, 12-16.
Christian Nanga Chick, Yusuke Sasaki, Mari Kawaguchi,* Eri Tanaka, Takako
Niikura,* Toyonobu Usuki*
"LC-MS/MS Quantitation of Elastin Crosslinker Desmosines and Histological
Analysis of Skin Aging Characteristics in Mice"
Bioorganic & Medicinal Chemistry 2023, 90, 117351.
Hiroaki Tanaka, Toyonobu Usuki*
"Synthesis of Elastin Crosslinker Desmosines" (Review)
Heterocycles 2023, 106, 1099-1131.
Kaho Oishi, Natsuki Mori, Riki Anzawa, Toyonobu Usuki*
"Synthesis of Lysinonorleucine and Mass Spectrometric Analysis of
Lysinonorleucine and Merodesmosine in Bovine Ligament and Eggshell Membrane"
Archives of Biochemistry and Biophysics 2023, 740, 109585.
臼杵 豊展
"Cynaropicrinの全合成と構造活性相関"
有機合成化学協会誌 2023, 81, 213-219.
Christian Nanga Chick, Tomoo Inoue,* Natsuki Mori, Eri Tanaka, Mari Kawaguchi,
Toshiyuki Takahashi, Junya Hanakita, Manabu Minami, Ryo Kanematsu, Toyonobu
Usuki*
"LC-MS/MS Analysis of Elastin Crosslinker Desmosines and Microscopic
Evaluation in Clinical Samples of Patients with Hypertrophy of Ligamentum
Flavum"
Bioorganic & Medicinal Chemistry 2023, 82, 117216.
Lokadi Pierre Luhata, Zixin Deng, Eri Tanaka, Toyonobu Usuki*
"In Vitro DPPH Radical Scavenging Activity of a-Pyrones from Odontonema strictum (Acanthaceae)"
Journal of Oleo Science 2023, 72, 571-576.
Riki Anzawa, Eri Shiratsuchi, Kenji Miyanari, Christian Nanga Chick, Ayame
Mikagi, Michio Yamada, Toyonobu Usuki*
"LC-MS/MS Analysis of Desmosine and Isodesmosine in Skipjack Tuna
"Katsuo" Elastin"
European Food Research and Technology 2023, 249, 829-834.
Akane Yamagishi, Yuki Egoshi, Makoto T. Fujiwara*, Noriyuki Suzuki, Tohru
Taniguchi, Ryuuichi D. Itoh, Yumiko Suzuki, Yoshiro Masuyama, Kenji Monde,
Toyonobu Usuki*
"Total Synthesis, Absolute Configuration, and Phytotoxic Activity
of Foeniculoxin"
Chemistry - A European Journal 2023, 29, e202203396.
【Highlighted in ChemistryViews】
【Highlighted in ChemStation】
Ayame Mikagi, Ryosuke Tashiro, Tomoo Inoue*, Riki Anzawa, Akiho Imura,
Takahiro Tanigawa, Tomohisa Ishida, Takashi Inoue, Kuniyasu Niizuma*, Teiji
Tominaga, Toyonobu Usuki*
"Isotope-dilution LC-MS/MS Analysis of the Elastin Crosslinkers Desmosine and Isodesmosine in Acute Cerebral Stroke Patients"
RSC Advances 2022, 12, 31769.
Tamao Saito*, Tomoyuki IIjima, Kohei Koyama, Tomonori Shinagawa, Ayaka
Yamanaka, Tsuyoshi Araki, Noriyuki Suzuki, Toyonobu Usuki, Robert R. Kay*
"Generating Polyketide Diversity in Dictyostelium: a Steely Hybrid
Polyketide Synthase Produces Alternate Products at Different Development
Stages"
Proceedings of the Royal Society B 2022, 289, 20221176.
Kaho Oishi, Nao Tanaka, Toyonobu Usuki*
"Total Synthesis of Merodesmosine"
Tetrahedron Letters 2022, 107, 154106.
Kogaku Kimura, Toyonobu Usuki*
"Synthesis of (1Z)-Deacylcnicin"
Tetrahedron Letters 2022, 107, 154102.
Hiroaki Tanaka, Seiya Miyagi, Yusuke Yoshida, Justin Steven Lamb, Christian
Nanga Chick, Lokadi Pierre Luhata, Mizuho Shibata, Eri Tanaka, Yumiko Suzuki,
Toyonobu Usuki*
"Synthesis and Biological Evaluation of Umifenovir Analogues as Anti-SARS-CoV-2
Agents"
ChemistrySelect 2022, 7, e202202097.
Lokadi Pierre Luhata, Christian Nanga Chick, Natsuki Mori, Kunihito Tanaka, Hiroshi Uchida, Takashi Hayashita, Toyonobu Usuki*
"Synthesis and Antioxidant Activity of Silver Nanoparticles using the Odontonema strictum Leaf Extract"
Molecules 2022, 27, 3210.
Natsuki Mori, Toyonobu Usuki*
"Extraction of Essential Oils from Tea Tree (Melaleuca alternifolia) and Lemon Grass (Cymbopogon citratus) using Betain-Based Deep Eutectic Solvent (DES)"
Phytochemical Analysis 2022, 33, 831-837.
Takahiro Suzuki, Nao Tanaka, Hiroaki Tanaka, Toyonobu Usuki*
"Middle-Scale IsoChichibabin Desmosine Synthesis"
Heterocycles 2022, 104, 961-968.
Lokadi Pierre Luhata, Toyonobu Usuki*
"Free Radical Scavenging Activities of Verbascoside and Isoverbascoside
from the Leaves of Odontonema strictum (Acathaceae)"
Bioorganic & Medicinal Chemistry Letters 2022, 59, 128528.
Seiya Miyagi, Reiko Yokoo, Takahiro Tanigawa, Dinda B. Pitna, Mika Hirose,
Toyonobu Usuki*
"Synthesis of Desmosine-BSA/KLH Conjugates via Sonogashira/Negishi
Cross-Coupling Reactions"
Tetrahedron Letters 2022, 90, 153616.
Mika Hirose, Toyoaki Kobayashi, Nao Tanaka, Ayame Mikagi, Hiroshi Wachi,
Yuki Mizutani, Toyonobu Usuki*
"IsoChichibabin Desmosine-13C3,15N1 Synthesis and Quantitative LC-MS/MS Analysis of Desmosine and Isodesmosine in Human Skin"
Bioorganic & Medicinal Chemistry 2021, 52, 116519.
Rina Yasutomi, Riki Anzawa, Masamitsu Urakawa, Toyonobu Usuki*
"Effective Extraction of Limonene and Hibaene from Hinoki (Chamaecyparis obtusa) using Ionic Liquid and Deep Eutectic Solvent"
Molecules 2021, 26, 4271.
Dinda B. Pitna, Nao Tanaka, Toyonobu Usuki*
"Pd/C-Catalyzed One-pot Suzuki-Miyaura Cross-Coupling/Hydrogenation
of Pyridine Derivatives"
Journal of Heterocyclic Chemistry 2021, 58, 2039-2044.
Lokadi Pierre Luhata*, Toyonobu Usuki*
"Antibacterial Activity of b-Sitosterol Isolated from the Leaves of Odontonema strictum (Acathaceae)"
Bioorganic & Medicinal Chemistry Letters 2021, 48, 128248.
Mika Hirose, Nao Tanaka, Toyonobu Usuki*
"Chichibabin/IsoChichibabin Pyridinium Synthesis of Ma'edamines C
and D"
Bioorganic & Medicinal Chemistry Letters 2021, 46, 128165.
Tenma Nakamura, Dinda B. Pitna, Kogaku Kimura, Yukiko Yoshimoto, Tomoya
Uchiyama, Takaya Mori, Ryosuke Kondo, Shihori Hara, Yuki Egoshi, Shoya
Yamaguchi, Noriyuki Suzuki, Yumiko Suzuki, Toyonobu Usuki*
"Total Synthesis of Cynaropicrin"
Organic & Biomolecular Chemistry 2021, 19, 6038-6044.
【Featured as HOT article collection】
【Selected as front cover】
【Highlighted in Organic Chemistry Portal】
Yuki Mizukawa, Mayumi Ikegami-Kawai*, Masako Horiuchi, Marcel Kaiser, Masayoshi Kojima, Seiki Sakanoue, Seiya Miyagi, Christian Nanga Chick, Hiroyuki Togashi, Masayoshi Tsubuki, Masataka Ihara, Toyonobu Usuki*, Isamu Itoh*
"Quest for a Potent Antimalarial Drug Lead: Synthesis and Evaluation
of 6,7-Dimethoxyquinazoline-2,4-diamines"
Bioorganic & Medicinal Chemistry 2021, 33, 116018.
Natsima Viriyaadhammaa, Aroonchai Saiai, Waranya Neimkhum, Wariya Nirachonkul, Wantida Chaiyana, Sawitree Chiampanichayalul, Singkome Tima, Toyonobu Usuki, Suwit Duangmano*, Songyot Anuchapreeda*
"Cytotoxic Antiproliferative Effects of Diarylheptanoids Isolated from Curcuma comosa Rhizomes on Leukaemic Cells"
Molecules 2020, 25, 5476.
Aisya Syahmina, Toyonobu Usuki*
"Ionic Liquid-Assisted Extraction of Essential Oils from Thujopsis dolobrata (Hiba)"
ACS Omega 2020, 5, 29618-29622.
Christian Nanga Chick, Tomoyo Misawa-Suzuki, Yumiko Suzuki, Toyonobu Usuki*
"Preparation and Antioxidant Study of Silver Nanoparticles of Microsorum pteropus Methanol Extract"
Bioorganic & Medicinal Chemistry Letters 2020, 30, 127526.
Nao Tanaka, Toyonobu Usuki*
"Can Heteroarenes/Arenes Be Hydrogenated over Catalytic Pd/C under
Ambient Conditions?"
European Journal of Organic Chemistry 2020, 34, 5514-5522.
【Cover Picture: Cover Feature】
【Highlighted in Synfacts 2020, 16, 1462; Synfacts.】
Songyot Anuchapreeda*, Riki Anzawa, Natsima Viriyaadhammaa, Waranya Neimkhum,
Wanida Chaiyana, Siriporn Okonogi*, Toyonobu Usuki*
"Isolation and Biological Activity of Agrostophillinol from Kaffir
Lime (Citrus hystrix) Leaves"
Bioorganic & Medicinal Chemistry Letters 2020, 30, 127256.
Mika Hirose, Reiko Yokoo, Daisuke Watanabe, Rina Suzuki, Miho Tanigawa,
Toyonobu Usuki*
"Synthesis of Multi-Deuterated Desmosine"
ChemistrySelect 2020, 5, 3843-3846.
Songyot Anuchapreeda*, Fah Chueahongthong, Natsima Viriyaadhammaa, Pawaret Panyajai, Riki Anzawa, Singkome Tima, Chadarat Ampasavate, Aroonchai Saiai, Methee Rungrojsakul, Toyonobu Usuki*, Siriporn Okonogi*
"Antileukemic Cell Proliferation of Active Compounds from Kaffir Lime
(Citrus hystrix) Leaves"
Molecules 2020, 25, 1300.
Daria A. Baut, Nao Tanaka, Reiko Yokoo, Toyonobu Usuki*
"Preparation of Isodesmosine-KLH Conjugate for ELISA System"
Chirality 2020, 32, 431-436.
【Special Issue in Memory and Honor of Professor Koji Nakanishi】
Toyonobu Usuki*, Yukiko Yoshimoto, Makiko Sato, Tae Takenaka, Ryota Takezawa,
Yusuke Yoshida, Masayuki Satake, Noriyuki Suzuki, Daisuke Hashizume, Sergei
V. Dzyuba
"Bilobalide and PC12 Cells: A Structure Activity Relationship Study"
Bioorganic & Medicinal Chemistry 2020, 28, 115251.
Jing Li, Yusuke Yoshida, Manami Kurita, Toyonobu Usuki*
"Cynaropicrin and Inhibition of NK-κB Activation: A Structure Activity
Relationship Study"
Bioorganic & Medicinal Chemistry Letters 2019, 29, 1518-1521.
Wakana Fuse, Akiho Imura, Nao Tanaka, Toyonobu Usuki*
"Chichibabin "Isodesmopyridine" Synthesis"
Tetrahedron Letters 2019, 60, 928-930.
Nao Tanaka, Toyonobu Usuki*
"Preparation of Protected 13Cn-Labeled Isodesmosines: Mechanistic Insight of Isodesmosine Formation"
Natural Product Communications 2019, 14, 1934578X19849967.
Hitomi Mizuno, Hibiki Yoshikawa, Toyonobu Usuki*
"Extraction of Nobiletin and Tangeretin from Peels of Shekwasha and
Ponkan using [C2mim][(MeO)(H)PO2] and Centrifugation"
Natural Product Communications 2019, 14, 1934578X19845816.
Akiho Imura, Nao Tanaka, Toyonobu Usuki*
"Chichibabin Pyridinium Synthesis"
Tetrahedron Letters 2019, 60, 489-492.
Anna P. Kondo, Takaaki B. Narita, Chihiro Murata, Tetsuhiro Ogura, Ayame
Mikagi, Toyonobu Usuki, Tamao Saito*
"4-Methyl-5-Pentylbenzene-1,3-Diol Regulates Chemotactic Cell Aggregation
and Spore Maturation via Different Mechanisms in Dictyostelium discoideum"
Current Microbiology 2019, 76, 376-381.
Quang Thuong Tran, Loan Thi Thanh Vu, Tram Huyen Le, Ly Thi Phuong Giang,
Toyonobu Usuki*
"Box-Behnken Experimental Design for the Extraction of Spinosin from Ziziphus mauritiana Lam. Seeds"
Asian Journal of Chemistry 2019, 31, 1045-1048.
Songyot Anuchapreeda, Nattakanwadee Khumpirapang, Sawitree Chiampanichayakul,
Wariya Nirachonkul, Aroonchai Saiai, Toyonobu Usuki*, Siriporn Okonogi*
"Characterization and Biological Properties of Zederone and Zedoarondiol
from Rhizomes of En-Lueang (Curcuma cf. amada)"
Natural Product Communications 2018, 13, 1615-1618.
Toyonobu Usuki*, Masahiro Yoshizawa-Fujita*
"Extraction and Isolation of Natural Organic Compounds from Plant
Leaves Using Ionic Liquids" in Advances in Biochemical Engineering/Biotechnology 2018
Springer, Berlin, Heidelberg
Ayame Mikagi, Dai Tokairin, Toyonobu Usuki*
"Suzuki-Miyaura Cross-Coupling Reaction of Monohalopyridines and L-Aspartic
Acid Derivative"
Tetrahedron Letters 2018, 59, 4602-4605.
Nao Tanaka, Manami Kurita, Yuko Murakami, Toyonobu Usuki*
"Chichibabin and IsoChichibabin Pyridinium Syntheses of Isodesmosine,
Desmosine, and their Derivatives"
European Journal of Organic Chemistry 2018, 21, 6002-6009.
臼杵 豊展
"ボーダーレス天然物化学"
有機合成化学協会誌 2018, 76, 422-425.
Hitomi Mizuno, Toyonobu Usuki*
"Ionic Liquid-Assisted Extraction and Isolation of Cynaropicrin and
Cnicin from Artichoke and Blessed Thistle"
ChemistrySelect 2018, 3, 1781-1786.
Songyot Anuchapreeda, Nattakanwadee Khumpirapang, Kawinnat Rupitiwiriya,
Leelawat Tho-iam, Aroonchai Saiai, Siriporn Okonogi, Toyonobu Usuki*
"Cytotoxicity and Inhibition of Leukemic Cell Proliferation by Sesquiterpenes
from Rhizomes of Mah-Lueang (Curcuma cf. viridiflora Roxb.)"
Bioorganic & Medicinal Chemistry Letters 2018, 28, 410-414.
Toyonobu Usuki*, Shingo Onda, Masahiro Yoshizawa-Fujita, Masahiro Rikukawa
"Use of [C4mim]Cl for Efficient Extraction of Caffeoylquinic Acids from Sweet Potato
Leaves"
Scientific Reports 2017, 7, 6890.
Toyonobu Usuki*, Koki Munakata
"Extraction of Essential Oils from the Flowers of Osmanthus fragrans var. aurantiacus Using an Ionic Liquid"
Bulletin of the Chemical Society of Japan 2017, 90, 1105-1110.
Toyonobu Usuki*, Akira Komatsu
"Preparation of Monoalkylpiperidines via the Mild Hydrogenation of
Monoalkynylpyridines"
Tetrahedron Letters 2017, 58, 2856-2858.
【Highlighted in Synfacts 2017, 13, 1224; Synfacts.】
Keita Ogawa, Takahiro Hayashi, Yong Y. Lin, Toyonobu Usuki*
"Synthesis of Desmosine-Containing Cyclic Peptide for the Possible
Elucidation of Elastin Crosslinking Structure"
Tetrahedron 2017, 73, 3838-3847.
Daisuke Watanabe, Rina Suzuki, Toyonobu Usuki*
"Synthesis of Desmosine-d4: Improvement of Isotopic Purity by D-H Exchange of Amino Groups"
Tetrahedron Letters 2017, 58, 1194-1197.
Koki Munakata, Masahiro Yoshizawa-Fujita, Masahiro Rikukawa, Toyonobu Usuki*
"Improved Extraction Yield of Citral from Lemon Myrtle Using a Cellulose-Dissolving
Ionic Liquid"
Australian Journal of Chemistry 2017, 70, 699-704.
Chihiro Murata, Masahiro Yoshizawa-Fujita, Masahiro Rikukawa, Toyonobu
Usuki*
"Extraction of Essential Oils from Lemongrass Using Ionic Liquid"
Asian Journal of Chemistry 2017, 29, 309-312.
Jiangtao He, Shuren Ma, Jerome Cantor, Toyonobu Usuki, Georgia Dolios, Rong Wang, Gerard M. Turino, Yong Y. Lin*
"Degradation of Human Lung Elastin Matrix"
Current Topics in Peptide & Protein Research 2016, 17, 105-124.
Manami Kurita, Miho Tanigawa, Shuhei Narita, Toyonobu Usuki*
"Synthetic Study of Cnicin: Synthesis of the Side Chain and its Esterification"
Tetrahedron Letters 2016, 57, 5899-5901.
Chihiro Murata, Quang Thuong Tran, Shingo Onda, Toyonobu Usuki*
"Extraction and Isolation of Ganoderic Acid S from Ganoderma lucidum"
Tetrahedron Letters 2016, 57, 5368-5371.
Chihiro Murata, Tetsuhiro Ogura, Shuhei Narita, Anna P. Kondo, Natsumi
Iwasaki, Tamao Saito, Toyonobu Usuki*
"Synthesis and SAR of 4-Methyl-5-Pentylbenzen-1,3-Diol (MPBD), Produced
by Dictyostelium discoideum"
Bioorganic & Medicinal Chemistry Letters 2016, 26, 1428-1433.
Takuya Sato, Shihori Hara, Makiko Sato, Keita Ogawa, Michael Adams, Toyonobu
Usuki*
"Synthesis of Cynaropicrin-d4"
Bioorganic & Medicinal Chemistry Letters 2015, 25, 5504-5507.
Ayano Tanaka-Yanuma, Satoshi Watanabe, Keita Ogawa, Sho Watanabe, Naoto
Aoki, Tetsuhiro Ogura, Toyonobu Usuki*
"Synthesis of the Polyketide Moiety of the Jamaicamides"
Tetrahedon Letters 2015, 56, 6777-6781.
Shingo Onda, Toyonobu Usuki*, Masahiro Yoshizawa-Fujita*, Masahiro Rikukawa
"Ionic Liquid-Mediated Extraction of Bilobalide from Ginkgo biloba Leaves"
Chemistry Letters 2015, 44, 1461-1463.
Yohei Koseki, Takanori Sugimura, Keita Ogawa, Rina Suzuki, Haruka Yamada, Noriyuki Suzuki, Yoshiro Masuyama, Yong Y. Lin, Toyonobu Usuki*
"Total Synthesis of Isodesmosine by Stepwise, Regioselective Negishi
and Sonogashira Cross-Coupling Reactions"
European Journal of Organic Chemistry 2015, 18, 4024-4032.
Takahiro Tanigawa, Akira Komatsu, Toyonobu Usuki*
"[13C3,15N1]-Labeled Isodesmosine: a Potential Internal Standard for LC-MS/MS Analysis
of Demosines in Elastin Degradation"
Bioorganic & Medicinal Chemistry Letters 2015, 25, 2046-2049.
Rina Suzuki, Hiroto Yanuma, Takahiro Hayashi, Haruka Yamada, Toyonobu Usuki*
"Syntheses of Natural and Deuterated Desmosines via Palladium-Catalyzed
Cross-Coupling Reactions"
Tetrahedron 2015, 71, 1851-1862.
Haruka Yamada, Takahiro Hayashi, Toyonobu Usuki*
"Total Synthesis of the COPD Biomarker Desmosine via Stepwise Sonogashira
Cross-Coupling Reactions"
Bulletin of the Chemical Society of Japan 2015, 88, 673-683.
Yuko Murakami, Rina Suzuki, Hiroto Yanuma, Jiantao He, Shuren Ma, Gerard
M. Turino, Yong Y. Lin, Toyonobu Usuki*
"Synthesis and LC-MS/MS Analysis of Desmosine-CH2, a Potential Internal Standard for the Degraded Elastin Biomarker Desmosine"
Organic & Biomolecular Chemistry 2014, 12, 9887-9894.
Takanori Sugimura, Akira Komatsu, Yohei Koseki, Toyonobu Usuki*
"Pr(OTf)3-promoted Chichibabin Pyridine Synthesis of Isodesmosine in H2O/MeOH"
Tetrahedon Letters 2014, 55, 6343-6346.
Stefanie Zimmermann, Gerda Fouche, Maria De Mieri, Yukiko Yoshimoto, Toyonobu
Usuki, Rudzani Nthambeleni, Christopher J. Parkinson, Christiaan van der
Westhuyzen, Marcel Kaiser, Matthias Hamburger, Michael Adams*
"Structure-Activity Relationship Study of Sesquiterpene Lactones and
Their Semi-Synthetic Amino Derivatives as Potential Antitrypanosomal Products"
Molecules 2014, 19, 3523-3538.
Toyonobu Usuki*, Takanori Sugimura, Akira Komatsu, Yohei Koseki
"Biomimetic Chichibabin Pyridine Synthesis of the COPD Biomarkers
and Elastin Cross-Linkers Isodesmosine and Desmosine"
Organic Letters 2014, 16, 1672-1675.
Toyonobu Usuki*, Makiko Sato, Shihori Hara, Yukiko Yoshimoto, Ryosuke Kondo,
Stefanie Zimmermann, Marcel Kaiser, Reto Brun, Matthias Hamburger, Michael
Adams
"Antitrypanosomal Structure-Activity-Relationship Study of Synthetic
Cynaropicrin Derivatives"
Bioorganic & Medicinal Chemistry Letters 2014, 24, 794-798.
Toyonobu Usuki*, Hiroto Yanuma, Takahiro Hayashi, Haruka Yamada, Noriyuki Suzuki, Yoshiro Masuyama
"Improved Negishi Cross-Coupling Reactions of an Organozinc Reagent
Derived from L-Aspartic Acid with Monohalopyridines"
Journal of Heterocyclic Chemistry 2014, 51, 269-273.
Yuki Egoshi, Ryosuke Kondo, Yukiko Yoshimoto, Toru Sugiyama, Toyonobu Usuki*
"Improved Synthesis of (R)-7-Hydroxycarbone from (S)-a-Pinene"
Tetrahedron Letters 2013, 54, 7029-7030.
臼杵 豊展
"COPDバイオマーカー診断法の確立を目指したエラスチン架橋アミノ酸類の創製"
有機合成化学協会誌 2013, 71, 891-899.
Shuren Ma, Gerard M. Turino, Takahiro Hayashi, Hiroto Yanuma, Toyonobu
Usuki, Yong Y. Lin*
"Stable Deuterium Internal Standard for the Isotope-Dilution LC-MS/MS
Analysis of Elastin Degradation"
Analytical Biochemistry 2013, 440, 158-165.
Satoshi Watanabe, Sho Watanabe, Naoto Aoki, Toyonobu Usuki*
"Synthesis of the Polyketide (E)-Olefin of the Jamaicamides"
Synthetic Communications 2013, 43, 1397-1403.
Tetsuhiro Ogura, Toyonobu Usuki*
"Total Synthesis of Acerogenins E, G and K, and Centrolobol"
Tetrahedron 2013, 69, 2807-2815.
Hiroto Yanuma, Toyonobu Usuki*
"Synthesis of Neodesmosine, a Crosslinking Pyridinium Amino Acid of
Elastin, via a Negishi Cross-Coupling"
Heterocycles 2013, 87, 55-63.
Shuhei Narita, Tetsuhiro Ogura, Toyonobu Usuki*
"Synthesis of Magnolignan, a New Pigment Lightening Component, via
a Suzuki-Miyaura Reaction"
Journal of Chemistry 2013, 2013, 686242 (5 pages).
Yuko Murakami, Hiroto Yanuma, Toyonobu Usuki*
"Total Synthesis of the Elastin Crosslinker (+)-Desmopyridine"
Tetrahedron: Asymmetry 2012, 23, 1557-1563.
Hiroto Yanuma, Toyonobu Usuki*
"Total Synthesis of the COPD Biomarker Desmosine via Sonogashira and
Negishi Cross-Coupling Reactions"
Tetrahedron Letters 2012, 53, 5920-5922.
Toyonobu Usuki*, Haruka Yamada, Takahiro Hayashi, Hiroto Yanuma, Yohei Koseki, Noriyuki Suzuki, Yoshiro Masuyama, Yong Y. Lin
"Total Synthesis of COPD Biomarker Desmosine that Crosslinks Elastin"
Chemical Communications 2012, 48, 3233-3235.
Tohru Taniguchi, Toyonobu Usuki*
"Circular Dichroism Spectroscopy" in Supramolecular Chemistry: From Molecules to Nanomaterials
Edited by Jonathan W. Steed, Philip A. Gale
John Wiley & Sons Ltd, Chichester, UK, 2012, pp 393-410.
Hiroshi Goto, Toyonobu Usuki*
"1H-NMR Analysis of Terpene Trilactones (TTLs) in Ginkgo Biloba: Green Female Leaves Contain the Most TTLs"
Phytochemical Analysis 2012, 23, 84-87.
Toyonobu Usuki*, Nanae Yasuda, Masahiro Yoshizawa-Fujita*, Masahiro Rikukawa
"Extraction and Isolation of Shikimic Acid from Ginkgo Biloba Leaves Utilizing an Ionic Liquid that Dissolves Cellulose"
Chemical Communications 2011, 47, 10560-10562.
【Featured on the website of the Royal Society of Chemistry magazine Chemistry World.】
Ayano Tanaka, Toyonobu Usuki*
"Synthesis of the Peptide Moiety of the Jamaicamides"
Tetrahedron Letters 2011, 52, 5036-5038.
Etsuko Suzuki, Makiko Sato, Ryota Takezawa, Toyonobu Usuki, Takashi Okada*
"The Facilitative Effects of Bilobalide, a Unique Constituent of Ginkgo Biloba, on Synaptic Transmission and Plasticity in Hippocampal Subfields"
The Journal of Physiological Science 2011, 61, 421-427.
Yohei Koseki, Haruka Yamada, Toyonobu Usuki*
"Efficient Synthesis of Benzyl 2-(S)-[(tert-Butoxycarbonyl)amino]-w-Iodoalkanoates"
Tetrahedron: Asymmetry 2011, 22, 580-586.
Ayano Tanaka, Yasuhiro Arai, Su-Nam Kim, Jungyeob Ham, Toyonobu Usuki*
"Synthesis and Biological Evaluation of Bilobol and Adipostatin A"
Journal of Asian Natural Products Research 2011, 13, 290-296.
Toyonobu Usuki*, Mari Kawai, Koji Nakanishi, George A. Ellestad*
"Calicheamicin g1I and Phenyl tert-Butyl Nitron (PBN): Observation of a Kinetic Isotope Effect by an ESR Study"
Chemical Communications 2010, 46, 737-739.
Masayuki Inoue*, Nayoung Lee, Keisuke Miyazaki, Toyonobu Usuki, Shigeru
Matsuoka, Masahiro Hirama*
"Critical Importance of the Nine-Membered F Ring of Ciguatoxin for
Potent Bioactivity: Total Synthesis and Biological Evaluation of F-Ring-Modified
Analogues"
Angewandte Chemie International Edition 2008, 47, 8611-8614.
Toyonobu Usuki*, Koji Nakanishi, George A. Ellestad*
"Spin-Trapping of the p-Benzyne Intermediates from Ten-Membered Enediyne Calicheamicin g1I"
Organic Letters 2006, 8, 5461-5463.
Masahiro Hirama*, Kimio Akiyama, Parthasarathi Das, Takashi Mita, Martin
J. Lear, Kyo-ichiro Iida, Itaru Sato, Fumihiko Yoshimura, Toyonobu Usuki,
Shozo Tero-Kubota
"Direct Observation of ESR Spectra of Bicyclic Nine-Membered Enediynes
at Ambient Temperature"
Heterocycles 2006, 69, 83-89.
Masayuki Inoue*, Toyonobu Usuki, Nayoung Lee, Masahiro Hirama*, Toshiyuki
Tanaka, Fumihito Hosoi, Shinji Ohie, Toshio Otani
"Antitumor Enediyne Chromoprotein C-1027: Mechanistic Investigation
of the Chromophore-Mediated Self-Decomposition Pathway"
Journal of the American Chemical Society 2006, 128, 7896-7903.
Toyonobu Usuki, Masayuki Inoue*, Kimio Akiyama, Masahiro Hirama*
"ESR Studies on DNA Cleavage Induced by Enediyne C-1027 Chromophore"
Bioorganic & Medicinal Chemistry 2005, 13, 5218-5224.
Toyonobu Usuki, Takashi Mita, Martin J. Lear*, Parthasarathi Das, Fumihiko
Yoshimura, Masayuki Inoue, Masahiro Hirama*, Kimio Akiyama*, Shozo Tero-Kubota
"Spin Trapping of 13C-Labeled p-Benzynes Generated by Masamune-Bergman Cyclization of Bicyclic Nine-Membered
Enediynes"
Angewandte Chemie International Edition 2004, 43, 5249-5253.
Toyonobu Usuki, Masayuki Inoue*, Masahiro Hirama*, Toshiyuki Tanaka*
"Rational Design of a Supra C-1027: Kinetically Stabilized Analogue
of the Antitumor Enediyne Chromoprotein"
Journal of the American Chemical Society 2004, 126, 3022-3023.
Toyonobu Usuki, Masayuki Inoue, Kimio Akiyama, Masahiro Hirama*
"Spin-trapping Study of DNA Cleavage Induced by Enediyne C-1027 Chromophore"
Chemistry Letters 2002, 31, 1148-1149.
Patents
臼杵豊展、田中尚 「環状化合物の製造方法」
特願2019-194685、特開2021-066707、2019年10月25日出願
臼杵豊展 「弾性繊維損傷マーカーの解析」
特願2018-206695、6436401、2018年11月1日出願
臼杵豊展、水野瞳、吉川響 「フラボノイドの抽出方法及び単離方法」
特願2018-089207、特開2019-196313、2018年5月7日出願
臼杵豊展 「同位体標識化合物の製造方法」
特願2018-086606、特開2019-189577、2018年4月27日出願
臼杵豊展 「複合体」
特願2018-054389、特開2019-167301、2018年3月22日出願
臼杵豊展 「デスモシンおよびイソデスモシンの製造方法」
特願2017-243119、特開2019-108304、2017年12月19日出願
臼杵豊展 「Process for Preparing Deuterium Isotope of Desmosine and Derivatives
Thereof」
特許10,280,143、2017年11月13日出願
臼杵豊展、水野瞳 「テルペン類の抽出方法」
特願2017-159612、特開2019-037913、特許6981644、2017年8月22日出願
臼杵豊展 「ピぺリジン化合物の製造方法」
特願2016-119877、特開2017-222611、特許6744622、2016年6月16日出願
Yong Y. Lin, Shuren Ma, Gerard M. Turino, Toyonobu Usuki 「弾性繊維損傷マーカーの解析」
PCT/US2014/036070、WO2014179408、特許6436401、2014年4月30日出願
臼杵豊展、藤田正博、音田慎吾 「カフェオイルキナ酸類抽出方法及びカフェオイルキナ酸類製造方法」
特願2014-092037、特開2015-209401、特許6466081、2014年4月25日出願
臼杵豊展 「化合物、これを用いた定量分析用標準物質およびデスモシン類の定量方法」
特願2014-055337、特開2015-178957、特許6233929、2014年3月18日出願
Toyonobu Usuki 「Method for Producing Desmosine, Isodesmosine, and Derivatives」
PCT/JP2014/051482、特許9556119、2014年1月24日出願
臼杵豊展 「デスモシン、イソデスモシン、およびその製造方法」
特願2013-018473、特開2014-559652、特許6233934、2013年2月1日出願
臼杵豊展、藤田正博、保田菜々絵 「シキミ酸取得方法及びシキミ酸製造方法」
特願2011-052211、特開2012-188374、特許5737751、2011年3月9日出願
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